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miR-143 Interferes with ERK5 Signaling, and Abrogates Prostate Cancer Progression in Mice

BACKGROUND: Micro RNAs are small, non-coding, single-stranded RNAs that negatively regulate gene expression at the post-transcriptional level. Since miR-143 was found to be down-regulated in prostate cancer cells, we wanted to analyze its expression in human prostate cancer, and test the ability of...

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Detalles Bibliográficos
Autores principales: Clapé, Cyrielle, Fritz, Vanessa, Henriquet, Corinne, Apparailly, Florence, Fernandez, Pedro Luis, Iborra, François, Avancès, Christophe, Villalba, Martin, Culine, Stéphane, Fajas, Lluis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763222/
https://www.ncbi.nlm.nih.gov/pubmed/19855844
http://dx.doi.org/10.1371/journal.pone.0007542