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Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line

Humans, birds, and some primates do not express the uric acid degrading enzyme urate oxidase (UOX) and, as a result, have plasma uric acid concentrations higher than UOX expressing animals. Although high uric acid concentrations are suggested to increase the antioxidant defense system and provide a...

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Detalles Bibliográficos
Autores principales: Cleveland, Beth M, Leonard, Stephen S, Klandorf, Hillar, Blemings, Kenneth P
Formato: Texto
Lenguaje:English
Publicado: Landes Bioscience 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763251/
https://www.ncbi.nlm.nih.gov/pubmed/20357931