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Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line
Humans, birds, and some primates do not express the uric acid degrading enzyme urate oxidase (UOX) and, as a result, have plasma uric acid concentrations higher than UOX expressing animals. Although high uric acid concentrations are suggested to increase the antioxidant defense system and provide a...
Autores principales: | Cleveland, Beth M, Leonard, Stephen S, Klandorf, Hillar, Blemings, Kenneth P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763251/ https://www.ncbi.nlm.nih.gov/pubmed/20357931 |
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