Excitotoxic insults lead to peroxiredoxin hyperoxidation

Post-mitotic neurons must have strong antioxidant defenses to survive the lifespan of the organism. We recently showed that neuronal antioxidant defenses are boosted by synaptic activity. Elevated synaptic activity, acting via the N-methyl-D-aspartate (NMDA) receptor, enhances thioredoxin activity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Léveillé, Frédéric, Soriano, Francesc X, Papadia, Sofia, Hardingham, Giles E
Formato: Texto
Lenguaje:English
Publicado: Landes Bioscience 2009
Materias:
Extra View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763254/
https://www.ncbi.nlm.nih.gov/pubmed/20357934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763254/
https://www.ncbi.nlm.nih.gov/pubmed/20357934

Ejemplares similares