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Functional Evolution of cis-Regulatory Modules at a Homeotic Gene in Drosophila

It is a long-held belief in evolutionary biology that the rate of molecular evolution for a given DNA sequence is inversely related to the level of functional constraint. This belief holds true for the protein-coding homeotic (Hox) genes originally discovered in Drosophila melanogaster. Expression o...

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Detalles Bibliográficos
Autores principales: Ho, Margaret C. W., Johnsen, Holly, Goetz, Sara E., Schiller, Benjamin J., Bae, Esther, Tran, Diana A., Shur, Andrey S., Allen, John M., Rau, Christoph, Bender, Welcome, Fisher, William W., Celniker, Susan E., Drewell, Robert A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763271/
https://www.ncbi.nlm.nih.gov/pubmed/19893611
http://dx.doi.org/10.1371/journal.pgen.1000709