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Functional Evolution of cis-Regulatory Modules at a Homeotic Gene in Drosophila
It is a long-held belief in evolutionary biology that the rate of molecular evolution for a given DNA sequence is inversely related to the level of functional constraint. This belief holds true for the protein-coding homeotic (Hox) genes originally discovered in Drosophila melanogaster. Expression o...
Autores principales: | Ho, Margaret C. W., Johnsen, Holly, Goetz, Sara E., Schiller, Benjamin J., Bae, Esther, Tran, Diana A., Shur, Andrey S., Allen, John M., Rau, Christoph, Bender, Welcome, Fisher, William W., Celniker, Susan E., Drewell, Robert A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763271/ https://www.ncbi.nlm.nih.gov/pubmed/19893611 http://dx.doi.org/10.1371/journal.pgen.1000709 |
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