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Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening

BACKGROUND -: Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins. Several previously described Fas ligand-interacting SH3 domain proteins turned out to be...

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Detalles Bibliográficos
Autores principales: Voss, Matthias, Lettau, Marcus, Janssen, Ottmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763855/
https://www.ncbi.nlm.nih.gov/pubmed/19807924
http://dx.doi.org/10.1186/1471-2172-10-53