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Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity

BACKGROUND: Autoimmune diabetes (T1D) onset is preceded by a long inflammatory process directed against the insulin-secreting β cells of the pancreas. Deciphering the early autoimmune mechanisms represents a challenge due to the absence of clinical signs at early disease stages. The aim of this stud...

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Detalles Bibliográficos
Autores principales: Regnault, Béatrice, Osorio y Fortea, José, Miao, Dongmei, Eisenbarth, George, Melanitou, Evie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763872/
https://www.ncbi.nlm.nih.gov/pubmed/19799787
http://dx.doi.org/10.1186/1755-8794-2-63