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Roles for the Conserved Spc105p/Kre28p Complex in Kinetochore-Microtubule Binding and the Spindle Assembly Checkpoint

BACKGROUND: Kinetochores attach sister chromatids to microtubules of the mitotic spindle and orchestrate chromosome disjunction at anaphase. Although S. cerevisiae has the simplest known kinetochores, they nonetheless contain ∼70 subunits that assemble on centromeric DNA in a hierarchical manner. De...

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Detalles Bibliográficos
Autores principales: Pagliuca, Cinzia, Draviam, Viji M., Marco, Eugenio, Sorger, Peter K., De Wulf, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764089/
https://www.ncbi.nlm.nih.gov/pubmed/19893618
http://dx.doi.org/10.1371/journal.pone.0007640