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Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome

The resolvase Sin regulates DNA strand exchange by assembling an elaborate interwound synaptosome containing catalytic and regulatory Sin tetramers, and an architectural DNA-bending protein. The crystal structure of the regulatory tetramer was recently solved, providing new insights into the structu...

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Detalles Bibliográficos
Autores principales: Rowland, Sally-J, Boocock, Martin R, McPherson, Arlene L, Mouw, Kent W, Rice, Phoebe A, Stark, W Marshall
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764113/
https://www.ncbi.nlm.nih.gov/pubmed/19508283
http://dx.doi.org/10.1111/j.1365-2958.2009.06756.x