Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target

Heme (Fe2+ protoporphyrin IX) is an essential molecule that has been implicated the potent antimalarial action of artemisinin and its derivatives, although the source and nature of the heme remain controversial. Artemisinins also exhibit selective cytotoxicity against cancer cells in vitro and in vi...

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Detalles Bibliográficos
Autores principales: Zhang, Shiming, Gerhard, Glenn S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764339/
https://www.ncbi.nlm.nih.gov/pubmed/19862332
http://dx.doi.org/10.1371/journal.pone.0007472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764339/
https://www.ncbi.nlm.nih.gov/pubmed/19862332
http://dx.doi.org/10.1371/journal.pone.0007472

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