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Influence of Overt Diabetes Mellitus on Cyclosporine Pharmacokinetics in a Canine Model
Background/Aims. Diabetic patients usually require more medications than their nondiabetic counterparts. This work examined the effect of hyperglycemia on the pharmacokinetic properties of cyclosporine in a diabetic dog model. Main Methods. Diabetes was induced using a streptozotocin/alloxan combina...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764377/ https://www.ncbi.nlm.nih.gov/pubmed/19859566 http://dx.doi.org/10.1155/2009/363787 |