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Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties
We report for the first time abnormalities in cardiac ventricular electrophysiology in a genetically modified murine model lacking the Scn3b gene (Scn3b(−/−)). Scn3b(−/−) mice were created by homologous recombination in embryonic stem (ES) cells. RT-PCR analysis confirmed that Scn3b mRNA was express...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764399/ https://www.ncbi.nlm.nih.gov/pubmed/19351516 http://dx.doi.org/10.1016/j.pbiomolbio.2009.01.005 |