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BRG1 directly regulates nucleosome structure and chromatin looping of the α globin locus to activate transcription

α globin expression must be regulated properly to prevent the occurrence of α-thalassemias, yet many questions remain unanswered regarding the mechanism of transcriptional activation. Identifying factors that regulate chromatin structure of the endogenous α globin locus in developing erythroblasts w...

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Detalles Bibliográficos
Autores principales: Kim, Shin-Il, Bresnick, Emery H., Bultman, Scott J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764439/
https://www.ncbi.nlm.nih.gov/pubmed/19696073
http://dx.doi.org/10.1093/nar/gkp677