Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: expression, design optimization, uptake mechanism and nuclear localization

Gene transfer to the corneal endothelium has potential in preventing corneal transplant rejection. In this study, we transfected mouse corneal endothelial cells (MCEC) with a class of novel arginine-rich oligopeptides. The peptides featured a tri-block design and mediated reporter gene expression in...

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Detalles Bibliográficos
Autores principales: Seow, Wei Yang, Yang, Yi-Yan, George, Andrew J. T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764440/
https://www.ncbi.nlm.nih.gov/pubmed/19692581
http://dx.doi.org/10.1093/nar/gkp651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764440/
https://www.ncbi.nlm.nih.gov/pubmed/19692581
http://dx.doi.org/10.1093/nar/gkp651

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