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Characterization of anti-NF-κB RNA aptamer-binding specificity in vitro and in the yeast three-hybrid system
RNA aptamers offer a potential therapeutic approach to the competitive inhibition of DNA-binding transcription factors. In previous reports we described in vitro selection and characterization of anti-NF-κB p50 and p65 RNA aptamers. We now describe the further characterization of these aptamers in v...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764441/ https://www.ncbi.nlm.nih.gov/pubmed/19696077 http://dx.doi.org/10.1093/nar/gkp670 |