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Characterization of anti-NF-κB RNA aptamer-binding specificity in vitro and in the yeast three-hybrid system

RNA aptamers offer a potential therapeutic approach to the competitive inhibition of DNA-binding transcription factors. In previous reports we described in vitro selection and characterization of anti-NF-κB p50 and p65 RNA aptamers. We now describe the further characterization of these aptamers in v...

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Detalles Bibliográficos
Autores principales: Wurster, Susan E., Bida, John Paul, Her, Yeng F., Maher, L. James
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764441/
https://www.ncbi.nlm.nih.gov/pubmed/19696077
http://dx.doi.org/10.1093/nar/gkp670