Sequence variant (CTAGGG)(n) in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

Short contiguous arrays of variant CTAGGG repeats in the human telomere are unstable in the male germline and somatic cells, suggesting formation of unusual structures by this repeat type. Here, we report on the structure of an intramolecular G-quadruplex formed by DNA sequences containing four huma...

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Detalles Bibliográficos
Autores principales: Lim, Kah Wai, Alberti, Patrizia, Guédin, Aurore, Lacroix, Laurent, Riou, Jean-François, Royle, Nicola J., Mergny, Jean-Louis, Phan, Anh Tuân
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://www.ncbi.nlm.nih.gov/pubmed/19692585
http://dx.doi.org/10.1093/nar/gkp630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764449/
https://www.ncbi.nlm.nih.gov/pubmed/19692585
http://dx.doi.org/10.1093/nar/gkp630

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