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Direct visualization of G-quadruplexes in DNA using atomic force microscopy

The formation of G-quadruplexes in G-rich regions of DNA is believed to affect DNA transcription and replication. However, it is currently unclear how this formation occurs in the presence of a complementary strand. We have used atomic force microscopy (AFM) to image stable RNA/DNA hybrid loops gene...

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Detalles Bibliográficos
Autores principales: Neaves, Kelly J., Huppert, Julian L., Henderson, Robert M., Edwardson, J. Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764456/
https://www.ncbi.nlm.nih.gov/pubmed/19696072
http://dx.doi.org/10.1093/nar/gkp679