Runx-CBFβ complexes control Foxp3 expression in regulatory T cells

Foxp3 plays an indispensable role in establishing stable transcriptional and functional programs of regulatory T (T(reg)) cells. Loss of Foxp3 expression in mature T(reg) cells results in a failure of suppressor function, yet the molecular mechanisms ensuring steady heritable Foxp3 expression in the...

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Detalles Bibliográficos
Autores principales: Rudra, Dipayan, Egawa, Takeshi, Chong, Mark M. W., Treuting, Piper, Littman, Dan R., Rudensky, Alexander Y.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764816/
https://www.ncbi.nlm.nih.gov/pubmed/19767756
http://dx.doi.org/10.1038/ni.1795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764816/
https://www.ncbi.nlm.nih.gov/pubmed/19767756
http://dx.doi.org/10.1038/ni.1795

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