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Runx-CBFβ complexes control Foxp3 expression in regulatory T cells

Foxp3 plays an indispensable role in establishing stable transcriptional and functional programs of regulatory T (T(reg)) cells. Loss of Foxp3 expression in mature T(reg) cells results in a failure of suppressor function, yet the molecular mechanisms ensuring steady heritable Foxp3 expression in the...

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Detalles Bibliográficos
Autores principales:	Rudra, Dipayan, Egawa, Takeshi, Chong, Mark M. W., Treuting, Piper, Littman, Dan R., Rudensky, Alexander Y.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764816/ https://www.ncbi.nlm.nih.gov/pubmed/19767756 http://dx.doi.org/10.1038/ni.1795

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