Arylamine N-Acetyltransferases in Mycobacteria

Polymorphic Human arylamine N-acetyltransferase (NAT2) inactivates the anti-tubercular drug isoniazid by acetyltransfer from acetylCoA. There are active NAT proteins encoded by homologous genes in mycobacteria including M. tuberculosis, M. bovis BCG, M. smegmatis and M. marinum. Crystallographic str...

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Detalles Bibliográficos
Autores principales: Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764864/
https://www.ncbi.nlm.nih.gov/pubmed/18680471
http://dx.doi.org/10.2174/138920008784892100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764864/
https://www.ncbi.nlm.nih.gov/pubmed/18680471
http://dx.doi.org/10.2174/138920008784892100

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