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Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy

Dysregulated inflammation contributes to disease pathogenesis in both the periphery and the brain. Cytokines are coordinators of inflammation and were originally defined as secreted mediators, released from expressing cells to activate plasma membrane receptors on responsive cells. However, a group...

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Detalles Bibliográficos
Autores principales: Luheshi, NM, Rothwell, NJ, Brough, D
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765320/
https://www.ncbi.nlm.nih.gov/pubmed/19681864
http://dx.doi.org/10.1111/j.1476-5381.2009.00331.x