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Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy
Dysregulated inflammation contributes to disease pathogenesis in both the periphery and the brain. Cytokines are coordinators of inflammation and were originally defined as secreted mediators, released from expressing cells to activate plasma membrane receptors on responsive cells. However, a group...
Autores principales: | Luheshi, NM, Rothwell, NJ, Brough, D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765320/ https://www.ncbi.nlm.nih.gov/pubmed/19681864 http://dx.doi.org/10.1111/j.1476-5381.2009.00331.x |
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