Cargando…

Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models

BACKGROUND: Tumour stromal myofibroblasts can promote tumour invasion. As these cells are genetically more stable than cancer cells, there has been enormous interest in developing targeted molecular therapies against them. Chloride intracellular channel 4 (CLIC4) and reactive oxygen species (ROS) ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Qin, Qu, Xun, Yang, Qifeng, Good, David A, Dai, Shuzhen, Kong, Beihua, Wei, Ming Q
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765417/
https://www.ncbi.nlm.nih.gov/pubmed/19781102
http://dx.doi.org/10.1186/1476-4598-8-78