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Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models
BACKGROUND: Tumour stromal myofibroblasts can promote tumour invasion. As these cells are genetically more stable than cancer cells, there has been enormous interest in developing targeted molecular therapies against them. Chloride intracellular channel 4 (CLIC4) and reactive oxygen species (ROS) ha...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765417/ https://www.ncbi.nlm.nih.gov/pubmed/19781102 http://dx.doi.org/10.1186/1476-4598-8-78 |