Evidence of HIV-1 adaptation to host HLA alleles following chimp-to-human transmission

BACKGROUND: The cytotoxic T-lymphocyte immune response is important in controlling HIV-1 replication in infected humans. In this immune pathway, viral peptides within infected cells are presented to T-lymphocytes by the polymorphic human leukocyte antigens (HLA). HLA alleles exert selective pressure...

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Detalles Bibliográficos
Autores principales: Ngandu, Nobubelo K, Seoighe, Cathal, Scheffler, Konrad
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765438/
https://www.ncbi.nlm.nih.gov/pubmed/19818146
http://dx.doi.org/10.1186/1743-422X-6-164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765438/
https://www.ncbi.nlm.nih.gov/pubmed/19818146
http://dx.doi.org/10.1186/1743-422X-6-164

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