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Evidence of HIV-1 adaptation to host HLA alleles following chimp-to-human transmission
BACKGROUND: The cytotoxic T-lymphocyte immune response is important in controlling HIV-1 replication in infected humans. In this immune pathway, viral peptides within infected cells are presented to T-lymphocytes by the polymorphic human leukocyte antigens (HLA). HLA alleles exert selective pressure...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765438/ https://www.ncbi.nlm.nih.gov/pubmed/19818146 http://dx.doi.org/10.1186/1743-422X-6-164 |