Cargando…

Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells

BACKGROUND: Ionizing radiation (IR) therapy is a primary treatment for glioblastoma multiforme (GBM), a common and devastating brain tumor in humans. IR has been shown to induce PI3K-Akt activation in many cell types, and activation of the PI3K-Akt signaling pathway has been correlated with radiores...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hui-Fang, Kim, Jung-Sik, Waldman, Todd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765447/
https://www.ncbi.nlm.nih.gov/pubmed/19828040
http://dx.doi.org/10.1186/1748-717X-4-43