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Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
BACKGROUND: Ionizing radiation (IR) therapy is a primary treatment for glioblastoma multiforme (GBM), a common and devastating brain tumor in humans. IR has been shown to induce PI3K-Akt activation in many cell types, and activation of the PI3K-Akt signaling pathway has been correlated with radiores...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765447/ https://www.ncbi.nlm.nih.gov/pubmed/19828040 http://dx.doi.org/10.1186/1748-717X-4-43 |