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Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells

BACKGROUND: Ionizing radiation (IR) therapy is a primary treatment for glioblastoma multiforme (GBM), a common and devastating brain tumor in humans. IR has been shown to induce PI3K-Akt activation in many cell types, and activation of the PI3K-Akt signaling pathway has been correlated with radiores...

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Detalles Bibliográficos
Autores principales:	Li, Hui-Fang, Kim, Jung-Sik, Waldman, Todd
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765447/ https://www.ncbi.nlm.nih.gov/pubmed/19828040 http://dx.doi.org/10.1186/1748-717X-4-43

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