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Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition

PURPOSE: To determine if cyclooxygenase-2 (COX-2) is upregulated when lens epithelial cells (LEC) in clinical samples of cataracts and posterior capsule opacification (PCO) undergo epithelial-mesenchymal transition (EMT)-like changes. We also wanted to learn if inhibition of the enzymatic activity o...

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Detalles Bibliográficos
Autores principales: Chandler, Heather L., Barden, Curtis A, Lu, Ping, Kusewitt, Donna F., Colitz, Carmen M. H.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765474/
https://www.ncbi.nlm.nih.gov/pubmed/17563718