Probing the bradycardic drug binding receptor of HCN-encoded pacemaker channels

I(f) (or I(h)), encoded by the hyperpolarization-activated, cyclic nucleotide-gated (HCN1–4) channel gene family, contributes significantly to cardiac pacing. Bradycardic agents such as ZD7288 that target HCN channels have been developed, but the molecular configuration of their receptor is poorly d...

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Detalles Bibliográficos
Autores principales: Chan, Yau-Chi, Wang, Kai, Wing Au, Ka, Lau, Chu-Pak, Tse, Hung-Fat, Li, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765624/
https://www.ncbi.nlm.nih.gov/pubmed/19756722
http://dx.doi.org/10.1007/s00424-009-0719-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765624/
https://www.ncbi.nlm.nih.gov/pubmed/19756722
http://dx.doi.org/10.1007/s00424-009-0719-2

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