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Probing the bradycardic drug binding receptor of HCN-encoded pacemaker channels
I(f) (or I(h)), encoded by the hyperpolarization-activated, cyclic nucleotide-gated (HCN1–4) channel gene family, contributes significantly to cardiac pacing. Bradycardic agents such as ZD7288 that target HCN channels have been developed, but the molecular configuration of their receptor is poorly d...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765624/ https://www.ncbi.nlm.nih.gov/pubmed/19756722 http://dx.doi.org/10.1007/s00424-009-0719-2 |