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Have last-observation-carried-forward analyses caused us to favour more toxic dementia therapies over less toxic alternatives? A systematic review

BACKGROUND: Intention-to-treat analysis is used in the analysis of randomized controlled trials to preserve trial power in the presence of missing subject data as well as to control for both known and unknown confounding factors. One form of intention-to-treat analysis is last-observation-carried-fo...

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Detalles Bibliográficos
Autores principales: Molnar, Frank J, Man-Son-Hing, Malcolm, Hutton, Brian, Fergusson, Dean A
Formato: Texto
Lenguaje:English
Publicado: Open Medicine Publications, Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765769/
https://www.ncbi.nlm.nih.gov/pubmed/19946392