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A Neutralizing Human Monoclonal Antibody Protects against Lethal Disease in a New Ferret Model of Acute Nipah Virus Infection

Nipah virus is a broadly tropic and highly pathogenic zoonotic paramyxovirus in the genus Henipavirus whose natural reservoirs are several species of Pteropus fruit bats. Nipah virus has repeatedly caused outbreaks over the past decade associated with a severe and often fatal disease in humans and a...

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Detalles Bibliográficos
Autores principales: Bossart, Katharine N., Zhu, Zhongyu, Middleton, Deborah, Klippel, Jessica, Crameri, Gary, Bingham, John, McEachern, Jennifer A., Green, Diane, Hancock, Timothy J., Chan, Yee-Peng, Hickey, Andrew C., Dimitrov, Dimiter S., Wang, Lin-Fa, Broder, Christopher C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765826/
https://www.ncbi.nlm.nih.gov/pubmed/19888339
http://dx.doi.org/10.1371/journal.ppat.1000642