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Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair
BACKGROUND: Lentiviral gene therapy vectors are now finding clinical application. In order to fully exploit their potential it is important that vectors are made as efficient and as safe as possible. Accordingly, we have modified a previously reported vector to improve RNA processing, minimise Human...
Autores principales: | Koldej, Rachel M, Anson, Donald S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765960/ https://www.ncbi.nlm.nih.gov/pubmed/19811661 http://dx.doi.org/10.1186/1472-6750-9-86 |
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