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“cAMP Sponge”: A Buffer for Cyclic Adenosine 3′, 5′-Monophosphate
BACKGROUND: While intracellular buffers are widely used to study calcium signaling, no such tool exists for the other major second messenger, cyclic AMP (cAMP). METHODS/PRINCIPAL FINDINGS: Here we describe a genetically encoded buffer for cAMP based on the high-affinity cAMP-binding carboxy-terminus...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766031/ https://www.ncbi.nlm.nih.gov/pubmed/19888343 http://dx.doi.org/10.1371/journal.pone.0007649 |