Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

MicroRNAs (miRNAs) regulate gene expression posttranscriptionally by interfering with a target mRNA's translation, stability, or both. We sought to dissect the respective contributions of translational inhibition and mRNA decay to microRNA regulation. We identified direct targets of a specific...

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Detalles Bibliográficos
Autores principales: Hendrickson, David G., Hogan, Daniel J., McCullough, Heather L., Myers, Jason W., Herschlag, Daniel, Ferrell, James E., Brown, Patrick O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766070/
https://www.ncbi.nlm.nih.gov/pubmed/19901979
http://dx.doi.org/10.1371/journal.pbio.1000238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766070/
https://www.ncbi.nlm.nih.gov/pubmed/19901979
http://dx.doi.org/10.1371/journal.pbio.1000238

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