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Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA
MicroRNAs (miRNAs) regulate gene expression posttranscriptionally by interfering with a target mRNA's translation, stability, or both. We sought to dissect the respective contributions of translational inhibition and mRNA decay to microRNA regulation. We identified direct targets of a specific...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766070/ https://www.ncbi.nlm.nih.gov/pubmed/19901979 http://dx.doi.org/10.1371/journal.pbio.1000238 |