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The Pivotal Roles of TIA Proteins in 5′ Splice-Site Selection of Alu Exons and Across Evolution

More than 5% of alternatively spliced internal exons in the human genome are derived from Alu elements in a process termed exonization. Alus are comprised of two homologous arms separated by an internal polypyrimidine tract (PPT). In most exonizations, splice sites are selected from within the same...

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Detalles Bibliográficos
Autores principales: Gal-Mark, Nurit, Schwartz, Schraga, Ram, Oren, Eyras, Eduardo, Ast, Gil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766253/
https://www.ncbi.nlm.nih.gov/pubmed/19911040
http://dx.doi.org/10.1371/journal.pgen.1000717