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Mbd3, a Component of NuRD/Mi-2 Complex, Helps Maintain Pluripotency of Mouse Embryonic Stem Cells by Repressing Trophectoderm Differentiation

Embryonic stem cells (ES cells) can differentiate into cells derived from all three germ layers and extraembryonic tissues. While transcription factors such as, Oct4 and Nanog are well known for their requirements for undifferentiated ES cell growth, mechanisms of epigenetic repression of germ layer...

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Detalles Bibliográficos
Autores principales: Zhu, Dongmei, Fang, Junshun, Li, Yanxin, Zhang, Jian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766630/
https://www.ncbi.nlm.nih.gov/pubmed/19888462
http://dx.doi.org/10.1371/journal.pone.0007684