Cargando…

Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene

BACKGROUND: DJ-1 forms part of the neuronal cellular defence mechanism against oxidative insults, due to its ability to undergo self-oxidation. Oxidative stress has been implicated in the pathogenesis of central nervous system damage in different neurodegenerative disorders including Alzheimer'...

Descripción completa

Detalles Bibliográficos
Autores principales: Keyser, Rowena J, van der Merwe, Lize, Venter, Mauritz, Kinnear, Craig, Warnich, Louise, Carr, Jonathan, Bardien, Soraya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767350/
https://www.ncbi.nlm.nih.gov/pubmed/19825160
http://dx.doi.org/10.1186/1471-2350-10-105