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Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene
BACKGROUND: DJ-1 forms part of the neuronal cellular defence mechanism against oxidative insults, due to its ability to undergo self-oxidation. Oxidative stress has been implicated in the pathogenesis of central nervous system damage in different neurodegenerative disorders including Alzheimer'...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767350/ https://www.ncbi.nlm.nih.gov/pubmed/19825160 http://dx.doi.org/10.1186/1471-2350-10-105 |