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Whole genome single nucleotide polymorphism based phylogeny of Francisella tularensis and its application to the development of a strain typing assay

BACKGROUND: A low genetic diversity in Francisella tularensis has been documented. Current DNA based genotyping methods for typing F. tularensis offer a limited and varying degree of subspecies, clade and strain level discrimination power. Whole genome sequencing is the most accurate and reliable me...

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Detalles Bibliográficos
Autores principales: Pandya, Gagan A, Holmes, Michael H, Petersen, Jeannine M, Pradhan, Sonal, Karamycheva, Svetlana A, Wolcott, Mark J, Molins, Claudia, Jones, Marcus, Schriefer, Martin E, Fleischmann, Robert D, Peterson, Scott N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767358/
https://www.ncbi.nlm.nih.gov/pubmed/19811647
http://dx.doi.org/10.1186/1471-2180-9-213