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Cancer phenotype as the outcome of an evolutionary game between normal and malignant cells

BACKGROUND: There is variability in the cancer phenotype across individuals: two patients with the same tumour may experience different disease life histories, resulting from genetic variation within the tumour and from the interaction between tumour and host. Until now, phenotypic variability has p...

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Detalles Bibliográficos
Autores principales: Dingli, D, Chalub, F A C C, Santos, F C, Van Segbroeck, S, Pacheco, J M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768082/
https://www.ncbi.nlm.nih.gov/pubmed/19724279
http://dx.doi.org/10.1038/sj.bjc.6605288