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Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin

BACKGROUND: A major obstacle to the successful management of pancreatic cancer is to acquire resistance to the existing chemotherapeutic agents. Resistance to gemcitabine, the standard first-line chemotherapeutic agent for advanced and metastatic pancreatic cancer, is mainly attributed to an altered...

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Detalles Bibliográficos
Autores principales: Bafna, S, Kaur, S, Momi, N, Batra, S K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768097/
https://www.ncbi.nlm.nih.gov/pubmed/19738614
http://dx.doi.org/10.1038/sj.bjc.6605285