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Atacicept in relapsed/refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study

BACKGROUND: Advanced multiple myeloma (MM) and Waldenström's macroglobulinemia (WM) are incurable B-cell malignancies. This is the first full clinical report of atacicept, a fusion protein that binds to and neutralises the B-cell survival factors, B-lymphocyte stimulator (BLyS) and A proliferat...

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Detalles Bibliográficos
Autores principales: Rossi, J-F, Moreaux, J, Hose, D, Requirand, G, Rose, M, Rouillé, V, Nestorov, I, Mordenti, G, Goldschmidt, H, Ythier, A, Klein, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768101/
https://www.ncbi.nlm.nih.gov/pubmed/19789533
http://dx.doi.org/10.1038/sj.bjc.6605241