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Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice
OBJECTIVE: Morbid obesity may be accompanied by diabetes and painful diabetic neuropathy, a poorly understood condition that is manifested by mechanical or thermal allodynia and hyperalgesia. Recent studies have highlighted the importance of T-type calcium channels (T-channels) in peripheral nocicep...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768156/ https://www.ncbi.nlm.nih.gov/pubmed/19651818 http://dx.doi.org/10.2337/db08-1763 |