Paradoxical Coupling of Triglyceride Synthesis and Fatty Acid Oxidation in Skeletal Muscle Overexpressing DGAT1

OBJECTIVE: Transgenic expression of diacylglycerol acyltransferase-1 (DGAT1) in skeletal muscle leads to protection against fat-induced insulin resistance despite accumulation of intramuscular triglyceride, a phenomenon similar to what is known as the “athlete paradox.” The primary objective of this...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li, Shi, Xiaojing, Choi, Cheol Soo, Shulman, Gerald I., Klaus, Katherine, Nair, K. Sreekumaran, Schwartz, Gary J., Zhang, Yiying, Goldberg, Ira J., Yu, Yi-Hao
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768165/
https://www.ncbi.nlm.nih.gov/pubmed/19675136
http://dx.doi.org/10.2337/db08-1096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768165/
https://www.ncbi.nlm.nih.gov/pubmed/19675136
http://dx.doi.org/10.2337/db08-1096

Ejemplares similares