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C. elegans as Model for the Study of High Glucose– Mediated Life Span Reduction

OBJECTIVE: Establishing Caenorhabditis elegans as a model for glucose toxicity–mediated life span reduction. RESEARCH DESIGN AND METHODS: C. elegans were maintained to achieve glucose concentrations resembling the hyperglycemic conditions in diabetic patients. The effects of high glucose on life spa...

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Detalles Bibliográficos
Autores principales: Schlotterer, Andreas, Kukudov, Georgi, Bozorgmehr, Farastuk, Hutter, Harald, Du, Xueliang, Oikonomou, Dimitrios, Ibrahim, Youssef, Pfisterer, Friederike, Rabbani, Naila, Thornalley, Paul, Sayed, Ahmed, Fleming, Thomas, Humpert, Per, Schwenger, Vedat, Zeier, Martin, Hamann, Andreas, Stern, David, Brownlee, Michael, Bierhaus, Angelika, Nawroth, Peter, Morcos, Michael
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768179/
https://www.ncbi.nlm.nih.gov/pubmed/19675139
http://dx.doi.org/10.2337/db09-0567