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C. elegans as Model for the Study of High Glucose– Mediated Life Span Reduction
OBJECTIVE: Establishing Caenorhabditis elegans as a model for glucose toxicity–mediated life span reduction. RESEARCH DESIGN AND METHODS: C. elegans were maintained to achieve glucose concentrations resembling the hyperglycemic conditions in diabetic patients. The effects of high glucose on life spa...
Autores principales: | Schlotterer, Andreas, Kukudov, Georgi, Bozorgmehr, Farastuk, Hutter, Harald, Du, Xueliang, Oikonomou, Dimitrios, Ibrahim, Youssef, Pfisterer, Friederike, Rabbani, Naila, Thornalley, Paul, Sayed, Ahmed, Fleming, Thomas, Humpert, Per, Schwenger, Vedat, Zeier, Martin, Hamann, Andreas, Stern, David, Brownlee, Michael, Bierhaus, Angelika, Nawroth, Peter, Morcos, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768179/ https://www.ncbi.nlm.nih.gov/pubmed/19675139 http://dx.doi.org/10.2337/db09-0567 |
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